British woman has world's first baby by full ovary transplant

<http://www.timesonline.co.uk/tol/life_and_style/health/article5133467.ece>http://www.timesonline.co.uk/tol/life_and_style/health/article5133467.ece
 


Mark Henderson, Science Editor, in San Francisco

A 38-year-old woman from London has given birth to the world's first 
baby conceived after a full ovary transplant.

The patient, who received an ovary donated by her identical twin 
sister, had a healthy daughter weighing 7lb 15oz today, delivered by 
Caesarean section.

The birth is the ninth reported worldwide after ovarian tissue was 
transplanted from one sister to another, but the first in which an 
entire ovary was used.

The woman, who lives in London but has German nationality, became 
infertile at the age of 15 when she suffered premature ovarian 
failure and went through the menopause. Her identical twin, however, 
remains fertile and agreed to donate an ovary to her sister.


Related Links

    * Clinic claims safer fertility method matches IVF
    * Frozen IVF embryos produce healthier children
    * Statins cut symptoms of polycystic ovary sydrome

The transplant was conducted last year in the United States by 
Sherman Silber, of the Infertility Centre of St Louis in Missouri, 
who has pioneered the delicate microsurgical procedure.

Dr Silber said that as the donor twin lives in Vancouver, Canada, the 
sisters had not seen each other for four years before the operation. 
"They were reunited in St Louis," he told the American Society for 
Reproductive Medicine conference in San Francisco. "It has been 
unbelievably exciting."

The success of the full transplant could create fresh reproductive 
options for cancer patients who wish to preserve their fertility 
during treatment that might leave them sterile. It could allow such 
women to have an ovary removed and frozen before they begin 
chemotherapy or radiotherapy, which could then be re-attached when 
she is given the all-clear.

It might technically be possible for healthy women to preserve their 
fertility in the same manner, so they can try to start a family in 
their 40s or later, though other options such as freezing eggs and 
slices of ovarian tissue are likely to be more popular for this purpose.

Transplants from woman to woman are generally possible at the moment 
between identical twins, as they share all their DNA. This means 
organs can be transplanted between the two without danger of 
rejection by the body's immune system, or immuno-suppressant drugs.

The first birth from transplanted ovary tissue took place in 2005, to 
Stephanie Yarber, an American woman, whose donor was her identical 
twin sister, Melanie Morgan.

Only one ovarian transplant has so far been reported between ordinary 
sisters who are not identical twins, in Belgium in 2007. Teresa 
Alvaro, who had an early menopause, started to menstruate again after 
receiving grafts of ovary tissue donated by her sister, Sandra.

Dr Silber said the full ovary transplant is likely to last longer 
than strips of ovarian tissue, perhaps for ten years rather than 
three. The first patient had the operation chiefly to restore her 
ovarian function and menstrual cycles, as she did not want to take 
hormone replacement therapy. She then became pregnant by a 
spontaneous conception.

Scientists caution that ovarian transplants from women to women are 
unlikely to benefit more than a few patients, mostly identical twins. 
For the operation to work, it is necessary to have a donor who is a 
precise tissue match. And as giving up ovarian tissue involves health 
and fertility risks to the donor, only women who have had their 
children, or do not want any, would be suitable candidates. Egg 
donation and other forms of fertility treatment are likely to remain 
the therapy of choice.

Dr Silber predicted that some women would want to use the technology 
to have ovaries stored and frozen to postpone motherhood for social 
reasons. He said: "We are in the midst of an infertility epidemic 
which has become an enormous public problem."

Young women could have an ovary frozen in their 20s, Dr Silber said. 
"They then have a young ovary that can be transplanted back at any 
time and extend fertility."

<*}}}>< <http://www.holypostage.com/>Holy Postage <*}}}><
<*}}}><<http://www.halfthekingdom.org/>Half the Kingdom!<*}}}><

Prayer for Unborn Life:
O GOD OF LIFE AND LOVE, You have given us the gift to participate 
with You to bring new life into the world.  But, all too often, the 
mother's womb, which should be a nursery of life, becomes instead a 
place of it's destruction.

Help us to remove this evil and ensure respect for all life made in 
Your image and likeness, called to fulfill its promise on this earth,
and destined to find a home with you for all eternity.

We ask this through Jesus Christ, Our Lord, Our God, Our Savior, and Our ALL.
Amen.


<*}}}>< <http://www.holypostage.com/>Holy Postage <*}}}><
<*}}}><<http://www.halfthekingdom.org/>Half the Kingdom!<*}}}><

Prayer for Unborn Life:
O GOD OF LIFE AND LOVE, You have given us the gift to participate 
with You to bring new life into the world.  But, all too often, the 
mother's womb, which should be a nursery of life, becomes instead a 
place of it's destruction.

Help us to remove this evil and ensure respect for all life made in 
Your image and likeness, called to fulfill its promise on this earth,
and destined to find a home with you for all eternity.

We ask this through Jesus Christ, Our Lord, Our God, Our Savior, and Our ALL.
Amen.

--~--~---------~--~----~------------~-------~--~----~
Please note that I do not send or open attachments sent to this list. 

You received this message because you are subscribed to the Google Groups 
"Catholics on Fire" group.
To post to this group, send email to [email protected]
To unsubscribe from this group, send email to [EMAIL PROTECTED]
For more options, visit this group at 
http://groups.google.com/group/Catholics-on-Fire

May the blessing of Jesus and our Blessed Mother be with you
-~----------~----~----~----~------~----~------~--~---

Reply via email to