Miracle 'teabag' helps stroke victim to speak again

<http://www.telegraph.co.uk/health/healthnews/3543937/Miracle-teabag-helps-stroke-victim-to-speak-again.html>http://www.telegraph.co.uk/health/healthnews/3543937/Miracle-teabag-helps-stroke-victim-to-speak-again.html
 




A stroke victim has regained the power of speech 
after doctors placed a device resembling a teabag 
filled with stem cells in his brain.



By Murray Wardrop
Last Updated: 7:35AM GMT 03 Dec 2008
Miracle 'teabag' helps stroke victim to speak again

Genetically modified stem cells fitted into a 
kind of 'tea bag' are implanted to the patient's 
brain where they are supposed to have an anti-inflammatory effect Photo: EPA

Walter Bast, 49, also regained the use of his 
right arm after the revolutionary treatment, 
which prevents brain cells from dying.

If further trials of the treatment are 
successful, it could be on the market in as 
little as five years, providing fresh hope for 
the 45,000 Britons each year who suffer a 
haemorrhagic stroke, where a blood vessel in the brain bursts.

Currently, the only option is surgery, which has 
a variable success rate. Half of surgery patients 
will die within a month and just one in 20 
patients will recover to the extent of Mr Bast.

The pioneering treatment, called CellBeads, 
involves cutting away part of the skull to tie 
off leaking blood vessels and remove blood from the brain.

Surgeons then insert the 2cm by 2cm 'teabag' 
filled with capsules stuffed with around a million stem cells.

The stem cells, taken from bone marrow, have been 
genetically engineered to make a drug known as 
CM1 that protects brain cells from dying. This 
lets the cells rejuvenate and repair the damage done by the stroke.

After around two weeks, doctors at the 
International Neuroscience-Institute in Hanover, 
Germany, removed the 'teabag', resulting in Mr 
Bast regaining his speech and the use of his right arm.

Speaking a week after the operation, the first of 
its kind in the world, Mr Bast, a mechanic, said: "I feel a lucky guy."

The so-called CellBeads treatment is the 
brainchild of scientists at the British medical 
technology firm Biocompatibles International, based in Farnham, Surrey.

The stem cells are encapsulated in beads to hide 
them from the immune system and ensure they are not rejected by the body.

Enclosing everything in the 2cm square 'teabag' 
ensures the surgeon can easily remove it at the end of the treatment period.

Mr Bast, who lives near Bremen in Germany, agreed 
to be the first to test the operation after 
suffering two strokes in quick succession.

His surgeon, Professor Thomas Brinker, said: "We 
see a recovery as good as this in only the 
minority of patients, so it is an encouraging 
start. It is important that we found no side-effects."

Dr Peter Stratford, of Biocompatibles, said a 
one-size-fits-all treatment could be stored in 
hospital freezers ready for use when required.

If effective, it could have a huge impact on 
patients' quality of life and save the NHS billions.

But stem cell scientists warned that many safety 
and ethical hurdles would have to be crossed 
before the treatment was accepted for widespread use.

Haemorrhagic strokes account for around 30 per 
cent of the 150,000 strokes in the UK each year.

Stroke is Britain's third biggest killer, after 
heart disease and cancer, and causes more 
disability than any other disease. It costs the 
economy about £7 billion a year, including NHS bills and lost productivity.

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