'Vitamin' for baby brain disorder

http://news.bbc.co.uk/2/hi/health/7950590.stm

Pills

A supplement may change the biochemistry of brain fluid

Researchers say taking a special vitamin supplement during pregnancy 
could prevent hydrocephalus - one of the most common birth brain defects.

Tests on rats showed a combination of folates dramatically reduced 
the rates of hydrocephalus - in which fluids build up in the brain's chambers.

They even seemed to work after the condition had started to develop.

But the work, published in the Journal of Neuropathology and 
Experimental Neurology, is still at an early stage.

[]

HYDROCEPHALUS
Excessive accumulation of cerebrospinal fluid in the cavities of the brain
Puts a harmful amount of pressure on tissues in the brain
Most obvious symptom is an unusually large head size. Other symptoms 
can include: vomiting, sleepiness, irritability, downward deviation 
of the eyes and seizures
Many children also display symptoms that can be mistaken for 
naughtiness, such as verbal aggression and swearing, hyperactivity, 
not paying attention and generally unusual behaviour
They may also experience learning difficulties at school
The team from the universities of Manchester and Lancaster hope to 
get permission to start clinical trials in pregnant women with babies 
diagnosed with hydrocephalus.

The supplement itself is not currently available, so they are also 
seeking the support of a pharmaceutical company willing to produce it 
as a pill.

At present hydrocephalus affects one in 1,000 live births. There is 
no satisfactory treatment for it other than surgical diversion of the 
fluid through a tube, known as a shunt, from the brain to the abdomen 
or heart.

However, shunts are permanent and prone to infection and blockage, 
which means patients may require several operations during their lifetime.

Most of those with by the condition have impaired mental and physical 
ability, although the effects can vary widely.

Chemical composition

The team also say they have shown it is the chemical composition of 
cerebrospinal fluid - rather than the fluid itself putting pressure 
on the brain - which causes the problems.

[]

[]
  Hydrocephalus can cause severe disability and learning 
difficulties, so the possibility of prevention through a specific 
vitamin supplement is exciting
[]

Andrew Russell
ASBAH

Lead researcher Jaleel Miyan said: "Cerebrospinal fluid is not a 
liquid which simply cushions the brain and carries chemicals around 
it. It is actively produced and transported and plays an essential 
biological role in developing the brain".

The combination of supplements appeared to stimulate this process.

At present women are advised to take folic acid - a synthetic 
substance found to prevent spina bifida - but this does not appear to 
promote brain cell growth in the same way as the combination.

Andrew Russell, head of the Association for Spina Bifida and 
Hydrocephalus, said: "Hydrocephalus can cause severe disability and 
learning difficulties, so the possibility of prevention through a 
specific vitamin supplement is exciting.

"ASBAH is helping with this ground-breaking research because many 
babies born with hydrocephalus today survive, but with a lifelong disability.

"However, a lot of further work is still needed to prove this 
approach is effective, through clinical trials."

Dr Imogen Montague, a spokeswoman for the Royal College of 
Obstetricians and Gynaecologists, said the study was "potentially 
very exciting".

"There are so few things we can currently do to decrease the 
incidence of birth defects so these findings are really to be welcomed.

"But we do have to be cautious about the results - extrapolating 
results from rats may be problematic, and we need to know both 
whether it works, and whether it is safe for use in humans. Any 
general use would still be a long way off."


<*}}}>< <http://www.holypostage.com/>Custom Faith-based U.S. Postage <*}}}><
+
<*}}}>< <http://astore.amazon.com/halthekin-20>Catholic on Amazon 
<*}}}>< <*}}}>< 
<http://www.halfthekingdom.org/on+allposters+today.html>on AllPosters 
today <*}}}><
+
<*}}}>< <http://www.holypostage.com/>Holy Postage <*}}}><
<*}}}><<http://www.halfthekingdom.org/>Half the 
<http://www.halfthekingdom.org/>Kingdom!<*}}}><
+
"A person is a person, no matter how small." Dr. Seuss


<*}}}>< <http://www.holypostage.com/>Custom Faith-based U.S. Postage <*}}}><
+
<*}}}>< <http://astore.amazon.com/halthekin-20>Catholic on Amazon 
<*}}}>< <*}}}>< 
<http://www.halfthekingdom.org/on+allposters+today.html>on AllPosters 
today <*}}}><
+
<*}}}>< <http://www.holypostage.com/>Holy Postage <*}}}><
<*}}}><<http://www.halfthekingdom.org/>Half the 
<http://www.halfthekingdom.org/>Kingdom!<*}}}><
+
"A person is a person, no matter how small." Dr. Seuss

--~--~---------~--~----~------------~-------~--~----~
Please note that I do not send or open attachments sent to this list. 

You received this message because you are subscribed to the Google Groups 
"Catholics on Fire" group.
To post to this group, send email to [email protected]
To unsubscribe from this group, send email to 
[email protected]
For more options, visit this group at 
http://groups.google.com/group/Catholics-on-Fire

May the blessing of Jesus and our Blessed Mother be with you
-~----------~----~----~----~------~----~------~--~---

Reply via email to