Special Yogurt Fights Stomach Ulcers

<http://www.newsmax.com/health/yogurt_stomach_ulcers/2009/03/23/194907.html?utm_medium=RSS>http://www.newsmax.com/health/yogurt_stomach_ulcers/2009/03/23/194907.html?utm_medium=RSS
 


Monday, March 23, 2009 9:28 AM

Results of the first human clinical studies 
confirm that a new yogurt fights the bacteria 
that cause gastritis and stomach ulcers with what 
researchers describe as almost vaccine-like effects.

Researchers have long known that yogurt, a 
fermented milk product containing live bacteria, 
is a healthy source of calcium, protein, and 
other nutrients. Some brands of yogurt are now 
made with “probiotics” ­ certain types of 
bacteria ­ intended to improve health. The new 
yogurt represents a unique approach to fighting 
stomach ulcers, which affect 25 million people in 
the United States alone, and is part of a growing 
“functional food” market that now generates $60 billion in sales annually.

“With this new yogurt, people can now enjoy the 
taste of yogurt while preventing or eliminating 
the bacteria that cause stomach ulcers,” says 
study coordinator Hajime Hatta, Ph.D., a chemist 
at Kyoto Women’s University in Kyoto, Japan.

The new yogurt is already on store shelves in 
Japan, Korea, and Taiwan. The study opens the 
door to possible arrival of the product in the U.S., the researchers suggest.

A type of bacteria called Helicobacter pylori (H. 
pylori) or over-use of aspirin and or other 
nonsteroidal antiinflammatory drugs, causes most 
stomach ulcers. H. pylori ulcers can be 
effectively treated and eliminated with 
antibiotics and acid suppressants. However, that 
simple regimen is unavailable to millions of 
poverty-stricken people in developing countries 
who are infected with H. pylori. New research 
also links childhood H. pylori infection to 
malnutrition, growth impairment and other health 
problems. As a result, scientists have been 
seeking more economical and convenient ways of dealing with these bacteria.

In the new study, Hatta and colleagues point out 
that H. pylori seems to rely on a protein called 
urease to attach to and infect the stomach 
lining. In an effort thwart that protein, or 
antigen, Hatta turned to classic vaccine-making 
technology. They injected chickens with urease 
and allowed the chickens’ immune systems to 
produce an antibody to the protein. The 
researchers then harvested the antibody, called 
IgY-urease, from chicken eggs. Hatta and 
colleagues theorized that yogurt containing the 
antibody may help prevent the bacteria from adhering to the stomach lining.

To test their theory, the scientists recruited 42 
people who tested positive for H. pylori. The 
volunteers consumed two cups daily of either 
plain yogurt or yogurt containing the antibody 
for four weeks. Levels of urea, a byproduct of 
urease, decreased significantly in the antibody 
group when compared with the control group, 
indicating reduced bacterial activity, the researchers say.

“The results indicate that the suppression of H. 
pylori infection in humans could be achieved by 
drinking yogurt fortified with urease antibody,” 
Hatta states. The antibody was eventually 
destroyed by stomach acid, but not before having its beneficial effect.

Although the yogurt appears less effective than 
antibiotics for reducing levels of H. pylori, it 
is a lot easier to take than medicine and can be 
eaten daily as part of regular dietary routine, 
Hatta says. The antibody does not affect the 
yogurt’s overall taste and does not cause any 
apparent adverse side effects, he notes.

But anti-ulcer yogurt is not for everyone, Hatta 
cautions. He notes that people who are allergic 
to milk or eggs should avoid the product. 
Although the yogurt contains egg yolk, which 
tends to have lower allergen levels than egg 
white, an allergy risk still exists, he adds.

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