The pill impairs muscle gains in young women

<http://uk.reuters.com/article/healthNewsMolt/idUKTRE53G41020090417?sp=true>http://uk.reuters.com/article/healthNewsMolt/idUKTRE53G41020090417?sp=true
 


Fri Apr 17, 2009 5:21pm BST

By Megan Rauscher

NEW YORK (Reuters Health) - Young women who use oral contraceptives 
(OC) may not get as much out of their weight-lifting routine as women 
who are not on the pill, according to a study released today, which 
suggests that OC use impairs muscle gains from resistance exercise 
training in women.

"The factors that explain the differences in the magnitude of the 
responses to resistance exercise training between individuals are 
largely unknown," Chang-Woock Lee, from Texas A&M University in 
College Station, told Reuters Health.

"The present study is meaningful in that we have identified a 
potential new factor that may be independently associated with the 
characteristics and variability of muscle responses to a controlled 
resistance exercise training program," the researcher added.

In the study, 73 generally healthy women between 18 and 31 years old 
participated in whole-body resistance exercises three times per week 
for 10 weeks. Thirty-four of the women used oral contraceptives and 
39 did not. The women were encouraged to eat enough protein to 
promote muscle growth.

According to the researchers, there were marked differences in lean 
muscle mass gains between the two groups. Lean muscle increased by 
just 2.1 percent in OC users compared with 3.5 percent in non-OC users.

Lee and colleagues presented their findings Friday at the American 
Physiological Society meeting, part of the Experimental Biology 2009 
scientific conference underway in New Orleans.

In a prepared statement from the meeting, the researchers acknowledge 
being "surprised at the magnitude of differences in muscle gains 
between the two groups, with the non-OC women gaining more than 60 
percent greater muscle mass than their OC counterpart."

Other muscle responses, such as strength gains and arm/leg 
circumferences, were similar between the OC and non-OC users.

Tests on the women also showed that blood levels of three 
muscle-building hormones were significantly lower and one 
muscle-breaking hormone was significantly higher in OC users than 
non-OC users, Lee said. These findings "could help explain" why OC 
users showed diminished muscle gains from resistance exercise training.

Summing up, Lee said: "Numerous health and performance benefits 
including improved exercise/athletic performance, body composition, 
esthetic beauty, and self-image can be attained from the increased 
muscle mass and strength associated with resistance exercise 
training. OC users may not be able to fully enjoy those benefits 
while experiencing impaired exercise performance and difficulties 
achieving athletic goals due to diminished muscle responses they get 
from resistance exercise training."

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