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Alex McPherson asked me to post this message for him. Best regards, Aaron
For research purposes, I am collecting reports and incidences of
mysterious small molecules ( or larger ) that have been unexpectedly
observed in electron density maps. I would like to know of these
occurrences even if the identification is not definitive, but only
speculative. I am not interested in molecules which are of obvious
biological relevance or which have been intentionally added to the
mother liquors ( such as coenzymes, inhibitors, essential ions,
biological effectors, etc. ). I am interested in cataloging other kinds
of molecules that unintentionally became bound to the macromolecule in
the crystal, or which form intermolecular, lattice interactions in the
crystal. I have in mind things such as buffer molecules, sugars,
cyogens, peptide fragments, oligosaccharides, oligonucleotides, reducing
agents, detergents, precipitating agents, or anything else that might
have been present, or somehow crept into the mother liquor. I would be
grateful for a short note ( or a reference if you had the courage to
publish it ) to [EMAIL PROTECTED] <mailto:[EMAIL PROTECTED]>.
Thanking you in advance.
Alex McPherson
