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Dear All : Sorry if anybody already post this question to the bulletin board, but I was unable to find it. I have a protein that crystallizes in a very big cell which contains 20 protein monomers of 300 aminoacids each. I have partially solve the structure by molecular replacemente with Phaser. I have tried to improve the model by Arp-Warp but when it runs I got a complain from Refmac5 saying that the number of residues is bigger than 50,000. This is because Arp-Warp generates dummy atoms in the initial point atom model that are considered as individual residues. Now the question : Is there any version of Refmac5 compiled for refining large structures with more than 50,000 residues ?. If not, how can I compile my refmac5 to avoid this error ?. Thank you everyone for your help. Cheers Francisco -- Francisco J. Enguita, Ph.D. Host-pathogen Interactions Group Macromolecular Crystallography Laboratory ITQB Ap. 127 2781-901 Oeiras Portugal Phone : +351-214469669 Fax : +351-214433644 Web : http://xtal.itqb.unl.pt
