Well - most anom scatterers or heavy atoms are more than 4A apart so 3A
data is plenty
Eleanor
Peter Adrian Meyer wrote:
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Hi All,
It looks like dual space methods seem to be a good way of finding
anomalous scattering sites, if there are a large number of them. As far
as I know, resolution limits are important for direct methods/dual space
methods because you need to assume that you have discrete peaks in the
maps, or the probability distribution doesn't apply (correct me if I'm
wrong here).
I'm aware of the ~1.4 Angstrom resolution limit for phasing all atoms by
direct methods; is there a comparible rule for finding anomalous
scatterers? Or do you just hope that your resolution (and usable
anomalous signal) are sufficient to allow for peak resolution?
Pete
Pete Meyer
Fu Lab
BMCB grad student
Cornell University
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