I used refmac5 to refine a structure out from MR. But it seems

the geometric parameters of the output model are really bad,

only 50% residues are in core region of Ramachandrans plot, all

output from procheck are not good, Rfree value of the model is about

45%.  Can someone give any suggestions? Is there any special

parameters needed when the refinement is on some initial moder?

I didn't met such problem on models that are almost correct.

 

Any help are thankful!

 

Yuhe Liang










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