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1. Throw them in together and see what happens
2. Create a fusion protein with a linker: http://tinyurl.com/8wryh

James

On Sunday 04 December 2005 03:29, you wrote:
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> ***          CCP4 home page http://www.ccp4.ac.uk         ***
>
>
> Hi all,  I'd appreciate feedback on how people got crystals of a
> complex of 2 proteins which have a weak binding constant.  From initial
> screening I got crystals of both members of the complex separately.
>
> Thanks in advance - Michal.
> ------------------------------------------------------------------------
> Dr. Michal Harel
> Dept. of Structural Biology          [EMAIL PROTECTED]
> Weizmann Inst. of Science                  tel:  972-8-9342647
> Rehovot 76100, ISRAEL                      fax:  972-8-9344159
> ------------------------------------------------------------------------

-- 
James Stroud
UCLA-DOE Institute for Genomics and Proteomics
Box 951570
Los Angeles, CA 90095

http://www.jamesstroud.com/

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