*** For details on how to be removed from this list visit the *** *** CCP4 home page http://www.ccp4.ac.uk ***
CCP4BB, Here is a summary of the responses I received regarding DLS machines. Thanks to everyone who responded to my email. *** As far as Wyatt is concerned, they have excellent support. Overall I would recommend the Dynapro cuvette reader with temp controller (really nice for protein melting temps), but would NOT recommend the plate reader. *** Wyatt is very good. I have been to their training. Everyone was nice and professional. They tried very hard to improve their software to be more user friendly. **** We have a Dynapro Wyatt DLS (earlier sold by protein solutions). There are several issues that remain worrisome- especially if you plan to have an HPLC attachment (as opposed to the stand-alone mode) and the price of the cuvette (non-standard size, and have to be procured from Wyatt). Photocor DLS is another option that you could try. The Viscotek DLS appears to be among the better ones. **** in our lab we are currently using the Zetasizer Nano S from Malvern Instruments. It's quite powerful and really easy to use. You can easily measure from low to high protein concentration in a high reproducible manner. Before we were using the DynaPro from Wyatt Technologie, I would not recommend you this machine. **** There is also RiNA, Laser Spectroscatter 201 (www.rna-network.com) I don't know about the availability in the US, though. www.rna-network.com **** Rebecca Rebecca Page Brown University Dept. of Molecular Biology, Cell Biology and Biochemistry Center for Genetics, Genomics and Proteomics Box G-E4 Providence, RI 02912 email: [EMAIL PROTECTED] ph: 401.863.6076 fx: 401.863.9653 http://www.brown.edu/mcb/rpage
