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PRELIMINARY ANNOUNCEMENT

Eighth International School on the Crystallography of Biological Macromolecules
Como (Italy), May 21-25, 2006

ORGANIZERS
Tassos Perrakis (NKI, The Netherlands) ([EMAIL PROTECTED])
Andrea Carfi (IRBM, Rome, Italy) ([EMAIL PROTECTED])
Stefania di Marco (IRBM, Italy) ([EMAIL PROTECTED])
Derek Logan (Lund University, Sweden) ([EMAIL PROTECTED])
Marjolein Thunnissen (Lund University, Sweden) ([EMAIL PROTECTED])

PRINCIPAL FUNDING
EU Network MAX-INF2 (contract 505977)

PURPOSE AND ORGANIZATION OF THE SCHOOL
The school will be open to about 200 participants and will focus on the application of X-ray crystallographic methods to the study of proteins and nucleic acids, with emphasis on the latest developments. The program will include lectures on protein expression an purification, crystallization, data collection and processing, synchrotron sources, phasing (MIR, MAD, direct methods and molecular replacement), phase improvement, model building, refinement and analysis of structural data. These methods sections will be complemented with seminars about new structures. It is expected that several contributions will come from participants who are encouraged to propose a title for a poster or oral contribution in their application letter.

LOCATION
The school will be held at Centro del Casino, Como, Italy. (http:// www.centrovolta.it/societ%C3%A0casino/societ%C3%A0casino.htm), which is located literally at centre of Como. Como can be reached comfortably by train (30-40 min. from Milan; 3-4 hours from Zurich and Basel) or by car via the A9-E36 motorway). This is a slightly different location to previous Schools, which have been held at Villa Olmo outside Como.

INVITED LECTURERS INCLUDE

Methods:
Pär Nordlund, Jan-Willem de Gier (Stockholm), Simon Davies, Jonathan Grimes, Ian Berry (Oxford), Christophe Romier (Strasbourg), Janet Newman (San Diego), Jochen Müller-Dieckmann, Sasha Popov, Manfred Weiss, Guillaume Evrard (Hamburg), José Antonio Perez, Raimond Ravelli (Grenoble), Bram Schierbeek (Delft), Gwyndaf Evans (Diamond), Clemens Schulze-Briese (SLS), Zbigniew Dauter (NCI), Harry Powell, Phil Evans, Randy Read (Cambridge), Gerard Bricogne (Global Phasing), Richard Morris (Norwich), Kim Henrick, Eugene Krissinel (EBI), Jorge Navaza (Gif-sur-Yvette), Garib Murshudov, Kevin Cowtan, Roberto Steiner (York), Karsten Suhre (Marseille), Paul Adams (Berkeley), George Sheldrick (Göttingen, Germany), Dale Tronrud (Oregon), Tom Terwilliger (Los Alamos), Thomas Schneider (Milan)

Structures:
Elena Conti (Heidelberg), F. Ray (Paris), Nenad Ban (Zürich), Jim Naismith (St. Andrews), Kay Diederichs (Konstanz), Bill Clemons (Caltech), Laurence Pearl (London), Piet Gros (Utrecht), Poul Nissen (Århus), Erica Mancini (Oxford)

PRELIMINARY PROGRAM AND REGISTRATION
Will be announced in the second half of January, but mark your diaries now!

The meeting will last from Sunday May 21st, 2006, to Thursday May 25th. A limited number of Ph.D. students will be eligible for subsidy. Those wishing to apply for such subsidy will be asked to submit a short CV and motivation at the time of application.

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