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          POSTDOCTORAL POSITION

"Molecular structural biology for nano-material development"

This interdisciplinary project aims at the design and production of protein building blocks for the development of nano-objects.

The candidate will be in charge of the molecular design, genetic manipulation, expression and purification of protein chimeras, which either bear functional groups or assemble spontaneously into nano-arrays. Tasks will also include the biophysical analysis of samples and X-ray crystallographic studies directed to validate the design principles. The successful applicant will work in the group of Olga Mayans at the Division of Structural Biology, Biozentrum (University of Basel), and the visualization and manipulation of nano-objects will be performed under the supervision of Laurent Kreplak in collaboration with the Swiss Nanoscience Center. The Division of Structural Biology at Biozentrum is fully equipped for the structural analysis of proteins and large assemblies using NMR, electron microscopy, atomic force microscopy and X-ray crystallography. A full range of protein expression systems are in operation for sample production and multiple biophysical techniques are available for sample characterization.

Requirements: a strong background in molecular biology, protein engineering and/or ab initio protein design is required as well as strong experience in protein production and purification. Initial familiarity with a structural or biophysical technique will be of distinct advantage, although full training in X-ray crystallography and microscopy techniques will be provided.

Applications should be in the form of a comprehensive CV, a one-page summary of past work and contact details for two referees.

Starting date: 1st July 2006

For enquiries and applications contact [EMAIL PROTECTED]

The search is now open and will continue until the position is filled.

University of Basel offers an international and stimulating environment for interdisciplinary research in nano-biosciences. Located at the interface of three countries and in the proximity of the Alps, Basel enjoys a richness of multicultural, recreational and sport activities.

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www.biozentrum.unibas.ch

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