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Why not use the free-lunch method rather than adding arbitrary noise? -- Tim Gruene Institut fuer anorganische Chemie Tammannstr. 4 D-37077 Goettingen GPG Key ID = A46BEE1A On Fri, 28 Apr 2006, Bart Hazes wrote: > *** For details on how to be removed from this list visit the *** > *** CCP4 home page http://www.ccp4.ac.uk *** > > > It depends on whether refmac uses Fobs or Fcalc in the denominator. I'm > sure this can be changed if experiments would show that padding with > zeroes is a good idea. Padding with "noise" (data with I/SigI ~ 1) may > be better. The TRUNCATE procedure slightly overestimates the weakest > Fobs by truncating the negative part of the intensity probability > distribution. Setting amplitudes to zero would cause a discontinuity > that could spell trouble. > > Bart >
