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All;

Could someone point me to a "how-to" on multi crystal
averaging using the CCP4 suite?  I have a problem with
two crystal forms, and would like to see if I can both
improve the density and break model bias from a
molecular replacement sol'n in one of the forms.

Specifically:

How does one typically generate the initial mask to
cut
out the SF's for the search in to derive the RT
matrices between the forms?  In my case, I have a
rough model in one of the two forms.

Does anyone have scripts for the entire process?  I
have seen a couple floating around, but none that go
from mask generation to final inputs to dmmulti.

Thanks,
Steve




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