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POSTDOCTORAL RESEARCH FELLOWSHIP in Protein Crystallography at the
University of Oslo (Ref. 06/6591/AQU, deadline June 8th 2006)

A postdoctoral research fellowship (financed by the Norwegian Research
Council, project title "Structural Glycobiology") is available at the
Department of Chemistry, The Faculty of Mathematics and Natural Sciences,
University of Oslo, in the group of Ute Krengel. Preferred starting date
is this fall (September 1st or soon thereafter). Pay grade depending on
qualifications (ca. 30-32 KNOK)

The postdoctoral project will be in the field of protein crystallography,
targeting human mucins. Mucins are the major glycoprotein components that
confer the mucous its viscous gel-like properties. By covering the
digestive, respiratory and urogenital tract, they help to protect the
epithelial cells from dehydration and injury as well as from bacterial
infection. These proteins are very challenging targets, as they are huge
and in addition highly glycosylated. We are currently focusing our work on
the oligomer-forming domains of the MUC2 mucin as well as on the lectin
domain of this protein, domains that are at the focus of attention for the
function of this protein.

The project is based on a collaboration with the laboratory of Professor
Gunnar C. Hansson at the Göteborg University, Sweden, a world expert on
mucin biology and function (www.medkem.gu.se/mucinbiology). This group has
a facility for large scale production of recombinant proteins that will be
used in the present project. The project will be pursued in a new lab in
Oslo, which has just recently been established. The new X-ray equipment
(Micromax-007HF from Rigaku) has only been installed three weeks ago and
has from the very start been in perfect working condition.
The candidate should be determined to enter such a challenging project and
in addition be a good team-player. She/he should preferentially have
experience in all aspects of protein crystallographic work, with solid
practical experience in protein purification and crystallization being of
particular importance.

In addition to working on the announced project, it is strongly encouraged
that the candidate starts to build up her/his own research profile during
this postdoctoral period.

No teaching duties enter into this position, however, the candidate may
take teaching responsibilities, should she/he wish to.

It might also be of interest (for dynamic couples) that one further
postdoctoral position will become available in the near future.

For appointment the requirement is a doctoral degree in chemistry,
biology, biochemistry, or other relevant disciplines.

For further information please contact: Assoc. Professor Ute Krengel, tlf.
+47 22 85 54 61, e-mail: [EMAIL PROTECTED]


Web announcement:
http://www.admin.uio.no/opa/ledige-stillinger/2006/vit/06-6591-AQU-MN-Chemistry-Postdoc.html


Application guidelines:

The application should include a CV (including in particular any
experience relevant to the position announced) as well as the names and
contact details of three references, together with a cover letter stating
why the applicant has a special interest in this position. Applicants
should also submit a list of published and unpublished works and certified
copies of certificates/diplomas. The application should include copies of
the applicants’ five most significant publications and a summary of the
importance of these works. For more information see:
http://www.uio.no/admhb/reglhb/personal/tilsettingvitenskapelig/guidelinespostdoctor.xml

Applications (marked with Ref. No. 06/6591/AQU) must be sent to The
Faculty of Mathematics and Natural Sciences, P. O. Box 1032 Blindern,
NO-0315 Oslo, Norway.

The cover letter and CV may be submitted by e-mail to
[EMAIL PROTECTED], whereas all supporting documentation must be
submitted by regular mail.

Application papers will not be returned, with the exception of original
publications.


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Ute Krengel, PhD
Chalmers University of Technology
Center for Structural Biology
Department of Chemistry and Bioscience
P.O.Box 462
SE-405 30 Göteborg, Sweden

Tel : +46 31 773 3237
Fax : +46 31 773 3910
e-mail : [EMAIL PROTECTED]
URL: http://www.csb.gu.se/ute
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