*** For details on how to be removed from this list visit the ***
*** CCP4 home page http://www.ccp4.ac.uk ***
Postdoctoral Position at the Institut de biologie structurale, Grenoble
(France) for a biochemist or a bio-crystallographer
A postdoctoral position will be open at the “Institut de biologie
structurale” (IBS) at Grenoble (France) next winter for two years. This
fellowship is attributed preferentially to a young scientist who has
completed his/her PhD in a laboratory not related to the Commissariat à
l’Energie Atomique (CEA) in the past two years.
This position is available for a biochemist or a bio-crystallographer. A
candidate with an expertise in DNA binding protein would be appreciated
but is not compulsory.
At the IBS, we have just joined a project on the molecular mechanisms
responsible for the radiation and dessication tolerance of the
Deinococcus deserti, bacteria isolated which are extremely resistant to
gamma radiations and drought. These bacteria possess very efficient DNA
repair systems to survive in such exceptional life conditions. The
origins of this remarkable resistance and the mechanisms of genome
repair of these organisms are still not elucidated (Cox & Battista,
2005). However, some proteins have already been identified in
Deinococcus radiodurans and are also present in D. deserti.
we have initiated preliminary expression tests of these proteins and
selected some conditions suitable for their biochemical and structural
study. Our goal is to determine the crystal structures of these first
candidates and to understand and define the mechanisms of radiation
resistance related to these proteins at the molecular level.
In the next future, other potential proteins will be studied in our lab
and in collaboration with the CEA at Cadarache.
The candidate will be involved in the purification, the DNA binding
assay and the crystallographic work.
The IBS has a great location for whom desires to work in structural
biology, with an international environment (ESRF, ILL, EMBL and the
newly Carl-Ivan Branden Building), an easy access to the available
platforms (crystallization and protein expression) and to the
synchrotron beamlines.
Grenoble is a medium size city with an easy way of life and a large
panel of outdoor activities and an intellectual life.
Candidates should send CV directly to Laurence Serre at the IBS before
the 1st of October 2006.
[EMAIL PROTECTED]
Tel: 33-(0)438 78 68 01
--
----------------------------------------------------------
Laurence Serre
Institut de Biologie Structurale
Laboratoire de Protéines Membranaires
41, rue Jules Horowitz
38027 Grenoble cedex 01, France
Tel: 33 (0) 438 78 68 01
Fax: 33 (0) 438 78 54 94
-------------oOOo----------------oOOo---------------------
