Yuhong
Mark Matthewson <[EMAIL PROTECTED]> wrote:
Hi folks,
I was puzzled as I went through the literature and could not find out why many esterases cannot catalyze the cleavage of an amide bond, while proteases can hydrolyze esters. Is there a structural basis why an esterase cannot hydrolyze an amide or peptide?
Would greatly appreciate your expertise and help.
Best regards,
Rick
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