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PLEASE DO NOT REPLY TO THIS MAIL - APPLY VIA THE WEB IF INTERESTED Pfizer currently has the following opportunities: Principal Scientist - Structural Biologist (R5-R6) Cambridge, MA - Req # 057758 Responsibilities will involve the development, validation, and implementation of SB platforms and SBDD strategies in addressing selectivity issues associated with kinase drug design; recordkeeping, SOPs and QC development. To qualify, you must have a PhD or PhD-level scientific abilities in X-ray crystallography; expertise in kinasestructural biology (SB) and structure-based drug design (SBDD); and solid experience in all aspects of protein crystallization and crystallography. Experience in kinase inhibitor design is highly preferred. Principal/Senior Principal Scientist -Structural Biology La Jolla, CA - Req # 057566 In the Department of Structural Biology you will be responsible for managing a highly experienced gene to crystal team comprising 4 scientists and its accompanying portfolio of several projects in the drive to establish robust crystallization platforms to support structure guided efforts within the Department. The successful candidate will have a PhD in Biochemistry, Molecular Biology, Structural Biology or a closely related discipline with six or more years of postdoctoral experience in delivering high quality protein reagents which enable structural biology efforts. This position requires significant depth and breadth of experience in all modern approaches to construct design, expression, purification, characterizing and crystallization of recombinant proteins in support of structure guided ligand design efforts. Principal Scientist Crystallographer (R5/R6) St. Louis, MO - Req # 57856 As a vital member of our Protein Crystallography Group, you will be involved in its work with cross-functional teams to solve structures of new drug targets and generate protein: ligand co-crystal structures. Responsibilities include determining and interpreting crystal structures, and presenting the results to interdisciplinary project teams. To qualify, you should have a PhD in Biochemistry, Chemistry, or a related field; 1 to 3 years post-doctoral crystallography experience in an academic or industrial research lab; a breadth of knowledge and expertise in macromolecular X-ray crystallography; and excellent communications and interpersonal skills. We offer competitive compensation, full benefits and talented professional colleagues...some of the best and brightest in the industry. To find out more about this position and submit your resume, visit our website at: www.pfizer.com/careers and search by the appropriate Req #. We invite you to visit our website, www.pfizer.com/careers to learn more about our people, our products and our plans for the future. Pfizer is proud to be an Equal Opportunity Employer and welcomes applications from people with different experiences, backgrounds and ethnicities.
