Senior Research Associate II, Protein Crystallography
Position Description
Abbott Bioresearch Center seeks a highly motivated protein chemist/protein crystallographer within the Structural Biology group of the Chemistry Department. ABC, located 45 minutes west of Boston in Worcester, Massachusetts, pursues vibrant research programs on both traditional, low molecular weight pharmaceuticals for immunological and inflammatory disease as well as monoclonal antibody pharmaceuticals for all Abbott therapeutic areas. You will perform hands-on experiments in all stages of protein crystal structure determination in support of ABC drug discovery, from protein production to dissemination of structural results. The addition of new projects requires additional capacity in all stages of structural biology support, especially protein purification. You will interface with scientists at all levels within Chemistry, other departments at ABC, and with colleagues at Abbott Park. Exciting opportunities for both scientific and career development exist.
Required Education, Experience & Skills
M.S. degree in an appropriate discipline
(e.g. chemistry, biochemistry, or physics) and 5+ years of experience in
a protein crystallography laboratory; B.S. degree candidates with additional
experience will also be considered. The job grade will be commensurate
with relevant experience.
Experience in a pharmaceutical
or biotechnology company environment is preferred. Demonstrated hands-on
expertise in purification and characterization of proteins is critical,
as is expertise in protein crystal production and optimization, and collection
and processing of x-ray diffraction data. Familiarity with diverse crystallographic
computing methodologies (LINUX operating system) is needed.
Ability and willingness to travel
to synchrotron radiation facilities for data collection is required. Strong
analytical and communication skills are a must, as is a strong desire to
work collaboratively in a multi-disciplinary structure-aided drug design
environment.
Desired Skills
Basic molecular biology techniques.
Implementation of robotic technologies. Determination and refinement of
crystal structures. Minor equipment maintenance and repair. Synchrotron
radiation data collection.
Applicants should submit their
curriculum vitae, listing names and contact information for three references,
electronically via the Abbott Careers website at:
https://jobs.brassring.com/EN/ASP/TG/cim_home.asp?sec=1&partnerid=281&siteid=50
Please reference Job Code: 37608BR
Email inquiries at [EMAIL PROTECTED]
are encouraged as well.
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David W. Borhani, Ph.D.
Structural Biology Group Leader
Chemistry Department
Abbott Bioresearch Center
Vox: 508-688-3944
Fax: 508-754-7784
Email: [EMAIL PROTECTED]
Smail: Abbott Bioresearch
Center, Inc.
100 Research Drive
Worcester, MA 01605 U.S.A.
http://abbott.com
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