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POST-DOCTORAL POSITIONS IN STRUCTURAL BIOLOGY
Several post-doctoral positions in the area of structural biology
are available in the laboratory of Dr. Mirek Cygler and funded by CIHR. The
research activities of the group focus on structural characterization of
proteins by crystallography and NMR spectroscopy to gain detailed
understanding of their mode of action. The ongoing projects include:
(1) structural and functional genomics of bacterial protein complexes,
(2) structural studies of bacterial GAG lyases, mammalian GAG
hydrolases, GAG sulfotransferases and other GAG modifying enzymes;
(3) structures of bacterial membrane proteins.
The candidates should have experience in either protein crystallography or
NMR spectroscopy, good background in biochemistry and experience in protein
purification. There is very good technical support in molecular biology,
protein purification and all computational aspects.
Our laboratory is very well equipped for all aspects of structural
work. In addition to in-house area detectors we have very good access to the
BM and ID beamlines at BNL. We have access to 500, 750 and 800 MHz NMR
spectrometers. Several liquid handling robots are utilized for cloning,
protein purification and crystallization. Our computing facilities include a
network of graphics workstations, servers and PCs, as well as a large Linux
cluster. The group includes several macromolecular crystallographers, NMR
spectroscopists, technicians and a computer specialist. The projects involve
interactions with other groups at McGill, Biotechnology Research Institute,
University of Montreal and others. The laboratory provides a challenging
environment, which promotes collaborative work within the laboratory and
outside.
Montreal is vibrant, multicultural city, with many cultural, social
and recreational activities. Excellent restaurants with variety of ethnic
foods, charm of the Old Montreal, famous summer jazz festival, good
cross-country and downhill skiing in the winter within 45 min from the city
and excellent biking paths in the summer. Good hiking in Adirondacks is only
2 hrs away.
For more information contact:
Dr. Mirek Cygler
Biotechnology Research Institute, NRC
And Department of Biochemistry, McGill University
6100 Royalmount Avenue
Montreal, Quebec H4P 2R2
Canada
tel: 514-496-6321
fax: 514-496-5143
email: [EMAIL PROTECTED]