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Post a picture - maybe someone has seen it before. Also, try filling it up
with waters to see if additional density springs up - sometimes not all
portions of the ligand can be visible initiall.

Artem

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Sent: Wednesday, November 08, 2006 5:05 PM
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Subject: [ccp4bb]: Identification of substrate based on density map

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Hello,

Does anybody have an idea how to identify a small molecule based on
density map? I have solved a structure at 1.7A and found a
mysterious fo-fc map at 3sigma. I believe it is the ligand
copurified with my protein. Is there a way to identify it in
addition to guess and try? I have done a lot of guessing and trying
without success.

Thanks.

Zhen

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