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Message posted on behalf of Human resources at Roche Please apply via the website - do not reply to me or ccp4bb! The following opportunity is available at our U.S. Pharmaceutical Headquarters in Nutley, NJ: Associate Principal Scientist, Macromolecular Structure Group At Roche, the utilization of protein structure is highly integrated into our drug discovery efforts. Consequently, we have a very active and productive X-ray crystallography group within Discovery Chemisty. We are seeking a motivated and enthusiastic candidate to join this group. The primary function of this scientist will be the crystallization of proteins with and without small molecule ligands, in preparation for data collection. Additional responsibilities include performing molecular biology experiments to design and prepare multiple constructs in parallel for new targets and targets that have proven reluctant to crystallize. This position actively interacts with a broad team of medicinal chemists, computational chemists, and biologists. The successful candidate will possess a Masters degree, or a Bachelors degree with at least two years of relevant research experience. Qualifications include being well-versed in state-of-the-art molecular biology techniques, specifically the preparation of multiple clones in parallel using tagged expression systems. Experience with such systems in a crystallography lab setting is a plus. The ideal candidate will also have experience in protein crystallization utilizing both manual and automated systems. Strong communication and interpersonal skills are a must. To apply, please visit our website at www.rocheusa.com/career, and refer to position code 4572. Hoffmann - LaRoche is an equal opportunity employer, fully committed to diversity in the workplace.
