POSTDOCTORAL POSITIONS, BERGER LAB
UNIVERSITY OF CALIFORNIA, BERKELEY
Structure, function, and regulation of protein/nucleic acid complexes
and machines
Postdoctoral positions in Structural Biology are available
immediately in the laboratory of Prof. James Berger at the University
of California, Berkeley for highly motivated individuals with a
strong interest in integrated approaches to problems in structural
biology. The Berger Lab merges a variety of imaging methods with
mechanistic biochemistry to dissect the assembly and function of
macromolecular assemblies and machines that control DNA replication,
chromosome superstructure, and other essential protein/nucleic acid
transactions. Projects include studies of replication initiation
factors, helicase/tranlocases, topoisomerases, primases, condensation
proteins, and a variety of regulatory ATPases. Questions of interest
revolve around topics such as protein dynamics, molecular remodeling,
higher-order assembly and organization, catalytic function,
small-molecule inhibition, and cellular mechanism. More information
is available at the lab website: http://bergerlab.berkeley.edu.
This positions are ideal opportunities for an experienced
crystallographer or cryo-electron microscopist interested in
continuing structural studies, but who would like to complement his
or her expertise with other, diverse tools for understanding the
mechanisms of a wide variety of nucleic acid-dependent protein
machines. The fellow would benefit from both the outstanding
environment in the lab and the highly collaborative Berkeley
community. The lab has extensive crystallographic resources,
including a newly constructed protein expression/crystallization core
as part of the Keck MacroLab Center, and dedicated time at a joint UC
Berkeley/UCSF MAD synchrotron beamline at the neighboring Advanced
Light Source (ALS).
Candidates should have (or expect) a Ph.D. in X-ray crystallography
or single particle electron microscopy, and an established
publication record from their doctoral work. Preference will be
given to those with experience in the structure determination of
protein/protein and/or nucleic-acid complexes. Extensive biochemical
experience with protein purification, functional characterization,
and co-expression methods is also plus.
Applicants should send a CV and letters of recommendation from three
or four references to:
James M. Berger
Professor of Biochemistry and Molecular Biology
Department of Molecular and Cell Biology
QB3 Institute
327B Hildebrand Hall #3220
University of California, Berkeley
Berkeley, CA 94707
Or email to:
[EMAIL PROTECTED]
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James M. Berger, Ph.D.
Professor of Biochemistry and Molecular Biology
Campus Office Location:
327B Hildebrand Hall
Mailing Address:
Dept. of Molecular and Cell Biology
Quantitative Biology Institute
University of California, Berkeley
237 Hildebrand Hall #3220
Berkeley, CA 94720-3220
Phone: 510-643-9483
Fax: 510-643-9290
Lab: 510-643-9491, 510-643-8893
Email: [EMAIL PROTECTED]
Web: http://berger.berkeley.edu/
