Dear all,

we have two immediate openings for 3 years postdoctoral positions at the Department of Structural Biology and Genomics of IGBMC.

The projects involve the production and the structural investigation of several nuclear receptor complexes through an integrative structural biology approach. The aim of the project is to address the drug- and DNA-dependent assembly and architecture of functional nuclear receptors complexes. For this, a range of techniques such as biochemistry, biophysical characterization, small angle x-ray and neutron scattering, x-ray crystallography and cryo-electron microscopy (cryo-EM) will be employed. Work will benefit from access to the Structural Biology and Genomics platform at IGBMC (cloning, purification, crystallization) and from the crystallographic and cryo-EM facilities (in particular: Rigaku-diffractometer (Micromax 007-HF generator and Saturn 944 CCD detector), Tecnai20 field-emission-gun electron microscope (that will be extended soon), high-resolution high-throughput scanner, computing facilities).

Candidates are expected to have a Ph.D. degree, a keen interest in structural biology, and should enjoy working as part of an interdisciplinary team. They should have a background in at least one of the following areas: molecular biology; biochemistry, in particular protein expression and purification and/or biochemical characterization of protein-DNA complexes; crystallography; single molecule cryo-EM/image processing.

For informal enquiries, please contact:

Dr Bruno Klaholz or Dr Isabelle Billas

emails:  [EMAIL PROTECTED] and [EMAIL PROTECTED]
Department of Structural Biology and Genomics
Institute of Genetics and Molecular and Cellular Biology
IGBMC - UMR 7104
1, rue Laurent Fries
BP 10142
67404 ILLKIRCH CEDEX
France
Tel. 0033.390.24.47.98 and 0033.388.65.33.02
Web sites:      http://www-igbmc.u-strasbg.fr
http://www-igbmc.u-strasbg.fr/recherche/Dep_BGS/Eq_DM http://www-igbmc.u-strasbg.fr/recherche/Dep_BGS/Eq_DMora/index_uk.html
                     http://igbmc.fr/Klaholz










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Dr. Bruno P. Klaholz
Département de Biologie et Génomique Structurales
Institut de Génétique et de Biologie Moléculaire et Cellulaire
IGBMC - UMR 7104
1, rue Laurent Fries
BP 10142
67404 ILLKIRCH CEDEX
FRANCE

Tel. from abroad: 0033.390.24.47.98
Tel. inside France: 03.90.24.47.98
Fax from abroad: 0033.388.65.32.76
Fax inside France: 03.88.65.32.76
e-mail: [EMAIL PROTECTED]
websites: http://igbmc.fr/Klaholz    http://www-igbmc.u-strasbg.fr/

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