Dear all,
we have two immediate openings for 3 years postdoctoral positions at the
Department of Structural Biology and Genomics of IGBMC.
The projects involve the production and the structural investigation of
several nuclear receptor complexes through an integrative structural
biology approach. The aim of the project is to address the drug- and
DNA-dependent assembly and architecture of functional nuclear receptors
complexes. For this, a range of techniques such as biochemistry,
biophysical characterization, small angle x-ray and neutron scattering,
x-ray crystallography and cryo-electron microscopy (cryo-EM) will be
employed. Work will benefit from access to the Structural Biology and
Genomics platform at IGBMC (cloning, purification, crystallization) and
from the crystallographic and cryo-EM facilities (in particular:
Rigaku-diffractometer (Micromax 007-HF generator and Saturn 944 CCD
detector), Tecnai20 field-emission-gun electron microscope (that will be
extended soon), high-resolution high-throughput scanner, computing facilities).
Candidates are expected to have a Ph.D. degree, a keen interest in
structural biology, and should enjoy working as part of an
interdisciplinary team. They should have a background in at least one of
the following areas: molecular biology; biochemistry, in particular protein
expression and purification and/or biochemical characterization of
protein-DNA complexes; crystallography; single molecule cryo-EM/image
processing.
For informal enquiries, please contact:
Dr Bruno Klaholz or Dr Isabelle Billas
emails: [EMAIL PROTECTED] and [EMAIL PROTECTED]
Department of Structural Biology and Genomics
Institute of Genetics and Molecular and Cellular Biology
IGBMC - UMR 7104
1, rue Laurent Fries
BP 10142
67404 ILLKIRCH CEDEX
France
Tel. 0033.390.24.47.98 and 0033.388.65.33.02
Web sites: http://www-igbmc.u-strasbg.fr
http://www-igbmc.u-strasbg.fr/recherche/Dep_BGS/Eq_DM
http://www-igbmc.u-strasbg.fr/recherche/Dep_BGS/Eq_DMora/index_uk.html
http://igbmc.fr/Klaholz
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Dr. Bruno P. Klaholz
Département de Biologie et Génomique Structurales
Institut de Génétique et de Biologie Moléculaire et Cellulaire
IGBMC - UMR 7104
1, rue Laurent Fries
BP 10142
67404 ILLKIRCH CEDEX
FRANCE
Tel. from abroad: 0033.390.24.47.98
Tel. inside France: 03.90.24.47.98
Fax from abroad: 0033.388.65.32.76
Fax inside France: 03.88.65.32.76
e-mail: [EMAIL PROTECTED]
websites: http://igbmc.fr/Klaholz http://www-igbmc.u-strasbg.fr/