Hi everyone,
Postdoctoral positions in x-ray crystallography is available starting Jan 2007.


*A.* Duration: 18 months+, financed by the Ile-de-France regional Funds.
No restrictions on applicants. Start Date: Jan 2007
*
B*. Duration: 36 months+, financed by the Pasteur Foundation NY USA. 45,000 USD /year American Citizenship required. Deadline for submitting competitive application 02/Feb/2007. Start date Fall 2007.

Description: Macromolecular x-ray crystallography of integrase-DNA complexes in site-specific recombination and other Protein-protein interactions. The biochemistry and structural details of these complexes will be determined in view characterizing their mechanism and for designing small molecule ligands and new molecular tools.
*Ref.* */Nature/ 440 1157-62 (2006)*.
Requirements: Ph.D. in Protein Crystallography, Biochemistry or Chemistry with experience in protein x-ray crystallography. Experience in MAD/MIR and synchrotron data collection, phasing and refinement. Experience with biophysical techniques such as fluorescence, calorimetry and ultra-centrifugation, or interest in applying these, will be helpful. We are equipped with Rigaku generators and Mar imaging plates, and Cartesian robotics for large scale crystallization. Access to the [EMAIL PROTECTED]

The Pasteur Institute is located in a very attractive area of Paris, providing a high quality of life/work combination, as well as, access to resources and interaction with the scientific community. Please submit: CV + contact info for 3 referees.

Person to contact:
D. Gopaul
Institut Pasteur
Departement de Biologie Structurale et Chimie
Laboratoire de Biochimie et Biophysique des Macromolecules
Bat. Metchnikoff, p3011
25 Rue du Docteur Roux
Paris, 75724 Cedex 15
France
Email address: [EMAIL PROTECTED]
Phone number: +33 (0) 1-45-68-85-98
Fax number:     +33 (0) 1-45-68-85-97

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Deshmukh (Michael) N. Gopaul, Ph.D.
Head, Bioch.&.Biophys.Macromol.Lab.
Institut Pasteur
Dept. Biol. Struct. & Chimie - URA CNRS 2185
Bat. Metchnikoff, Rm.3011    email: [EMAIL PROTECTED]
25 Rue du Docteur Roux       Tel: 33 (0) 1 45.68.85.98
F-75724, Paris CEDEX 15      Fax: 33 (0) 1 45.68.85.97
http://www.pasteur.fr/recherche/unites/Bbm/index.html

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