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Santarsiero, Bernard D. wrote:
> Christian is wrong that the signal/noise ratio changes. The unit cell is
> bigger but you also have three times as many reflections, so the
> signal/noise ratio doesn't change.
>   
Just to clarify. I did not mean that the signal/noise ratio changes
between the several indexing possibilities. I just wanted to point out
that solving i.e. a P2(1) crystal with four molecule per unit cell is
much easier than the high symmetric like R32 or P622 etc. with as many
as 54 molecules in the unit cell. Many molecules in the unit cell give a
low signal in the Patterson-correlation of the rotation function as far
as I know. But this are just my 2 cents. There are other people in the
community that may explain much better why some spacegroups give more
headache to solve than others.

best regards

Christian


 

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