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Hi Weikai,

I think xtriage or xprep might be of use here as well. Those programs do take 
merged data and make guesses about the space group. 

hth

Peter



----- Original Message -----
From: [EMAIL PROTECTED]
Date: Tuesday, January 9, 2007 3:42 am
Subject: [ccp4bb]: Pointless HKL2000 and unmerged data
To: [email protected]

> ***  For details on how to be removed from this list visit the  ***
> ***          CCP4 home page http://www.ccp4.ac.uk         ***
> 
> 
> 
> Hi All:
> 
> I am trying POINTLESS for detecting real space group using data 
> processedby HKL2000.  Apparently, POINTLESS cries for unmerged 
> data.  I understand
> using Mosflm might be the best in this case, but I am not familiar 
> withthe program.
> 
> So I did the following to rescue but not sure if it is the right 
> thing. 
> 1) Integrate (denzo) as P1 space group in HKL2000.  2) Scalepack 
> in P1
> with keyword "no merge".  3) Using COMBAT in CCP4 to covert to mtz and
> specify the input .sca file as "Scalepack file nomerged (no 
> partials)".
> What I am more curious about, is what exactly does "unmerged" 
> mean?  Does
> it mean not reduced to asymmetric unit?  Or something happened much
> earlier in data processing, like the "no partials" comment in 
> COMBAT seems
> to suggest?  If it is the latter case, why is it so important for 
> symmetryanalysis in POINTLESS?
> 
> Regards,
> 
> Weikai
> 

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