Hi Zhiyi, for ground state ATP analogues use AMP-PNP (or AMP-PCP) or ADP in complex with beryllium fluoride.
transition state like analogues can be formed with ADP in complex with aluminium fluoride or magnesium fluoride. ADP - nitrate has also been used as a transition state analogue, hope this helps, cheers, Matt Matthew Bowler MRC Dunn Human Nutrition Unit Wellcome Trust / MRC Building Hills Rd Cambridge CB2 2XY > Hi everyone, > > I want to know which ATP analogues are suitable and popular for > co-crystallization > with enzyme. > Thank you in advance. > > Best, > Zhiyi > > > > > ------------------------------ > Zhiyi Wei > > --------------------------------------------- > > Institute of Biophysics, Chinese Academy of Sciences > > 15 Datun Road, Chaoyang District > > Beijing, P.R.China, 100101 > > Tel:86-(0)10-64888465 > > Fax:86-(0)10-64888513 > > --------------------------------------------- > > School of Life Sciences, > > University of Science & Technology of China, > > Hefei, Anhui, P.R.China, 230026 > >
