I have a perl script to do this job.
The pdb file should contain your ligand. 

Simplest way to run it is "lig_contact file.pdb"
If the script does not find the ligand, you can switch to command line options.

The script prepares a pymol input file and fires it up to display the 
interactions.
After you close the pymol window you can see the pymol script file. The list of 
interactions is listed as "distance .?? = (ligand atom), (protein atom)." in 
this file. The '??' could be cc (hydrophobic interaction) or hb (hydrogen bond).

Thanks 
Abhinav 

 


-----Original Message-----
From: CCP4 bulletin board [mailto:[EMAIL PROTECTED] On Behalf Of mathias
Sent: Tuesday, February 27, 2007 10:44 AM
To: [email protected]
Subject: [ccp4bb] software to calculate VDW interactions between small molecule 
and protein

Dear all,

Can anyone of you guys recommend free software, or any open access  
internet server, to calculate VDW interactions of small molecules  
binding to protein. The only information I need is an output file  
which lists all amino acids of the target protein which make VDW  
interactions with the binding small molecule.
Thank you very much for your help and recommendations,

Mathias

Attachment: lig_contact
Description: lig_contact

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