Message from Eleanor Dodson
I am chairing a session at the ECM 24 to be held in Morocco at the end of
August on
*Advances in crystallographic phasing and refinement*
I am interpreting this as mostly to be about Macromoolecular studies.
There are 6 slots for speakers, 2 invited and 4 chosen from the
abstracts. Ralf Grosse-Kunsleve and Kevin Cowtan will be the invited
speakers. The distribution of nationalities in the applications is a bit
narrow, and it would be nice to have some more. If you are interested
could you contact the ECM web site
ECM24 website: www.ecm24.org <http://www.ecm24.org>
and let me know too.
There are bursaries available for the young who apply early!
Eleanor Dodson
Macromolecular crystallography is developing in several directions, and
> this symposium will address these.> One is driven by the great
improvement in data quality obtained for many > of the crystals. This
allows some experimental phases to be derived > quickly using small
measured differences for each observation. These > provide a challenging
starting point for phase improvement and > extension. Dr Cowtan has
contributed greatly to this technique. > Refinement methods are also
developing to exploit both the better data > and the derived phases.> >
Another is in the structures attempted by crystallographers. Larger and
> more complex systems are being crystallised which often do not yield
> very complete data, but can give important biological insights. These
> are challenging to refine; there needs to be new approaches to >
parameterisation and minimisation.> > And a third is in developing ways
to rescue information from imperfect > data, where there is twinning or
other crystallographic problems.> > >
