Post Doctoral Positions in Structural Biology at the University of Toronto
Post Doctoral positions in structural biology are available at the University of Toronto and the Structural Genomics Consortium (SGC). The positions consist mainly of utilizing high-throughput technologies to design constructs, purify samples, and crystallize proteins from targeted human proteins. In addition, fellows conduct follow-up experiments and initiate external collaborations in order to advance our understanding of the molecular function, biological role, and/or therapeutic potential of these proteins. Available for assistance if needed are various in-house resources, including 1) a molecular biology team that performs cloning and mutagenesis, 2) a biophysics group that characterizes catalytic and binding properties of proteins and performs limited library screening, and 3) a protein crystallography group that phases and refines crystal structures and assists in pursuing follow-up structural studies. Examples of proteins that are currently being targeted include those in the ubiquitylation system as well as proteases and tyrosine kinases involved in signal transduction. The SGC is a non-profit partnership with a mandate to solve and publish structures of medically relevant human proteins. Since its inception in 2004, the SGC has promptly and freely deposited 425 structures into the PDB and made coordinates and materials & methods for these structures available to the public without restriction. Candidates should email CV and cover letter to: [EMAIL PROTECTED] Sirano Dhe-Paganon Principal Investigator, Structural Genomics Consortium Assistant Professor, Department of Physiology University of Toronto, Banting&Best Inst 100 College Street, Room 511 Toronto, ON, M5G 1L5 416-946-3876 website <http://www.sgc.utoronto.ca/SGC-WebPages/sdp.php>
