Postdoctoral Position at UCSF -- Structural Biology of Kinase-Scaffold
Complexes
Seeking outstanding candidates for postdoctoral position at UCSF focused
on the structure and function of multi-protein cell signaling
complexes. We are interested in understanding how scaffolding proteins
and other protein-protein interactions organize MAP kinase signaling
cascades. Our lab employs a multidisciplinary approach involving
crystallography and other structural methods combined with enzyme
kinetics, genetics and cell biology to understand fundamental mechanisms
of signaling systems both in vitro and in vivo. Candidate should have
experience in crystallography, molecular biology and protein
biochemistry. Position is at the beautiful, state-of-the-art UCSF
Mission Bay Campus, and includes access to the UCB/UCSF ALS beamline.
Please send CV to Wendell Lim ([EMAIL PROTECTED]) and arrange to have
three letters of reference sent by email. Please write "Application for
Structural Biology Postdoctoral Position" in your subject header.
For more information see: http://www.ucsf.edu/limlab
or
Domains, Motifs, and Scaffolds: The Role of Modular Interactions in the
Evolution and Wiring of Cell Signaling Circuits
Roby P. Bhattacharyya, Attila Reményi, Brian J. Yeh, and Wendell A. Lim
Annual Review of Biochemistry 75, 655-680 (2006)
The Ste5 Scaffold Allosterically Modulates Signaling Output of the Yeast
Mating Pathway
Roby P. Bhattacharyya*, Attila Reményi*, Matthew C. Good, Caleb J.
Bashor, Arnold M. Falick, and Wendell A. Lim
Science 311, 822-826 (2006)
The role of docking interactions in mediating signaling input, output,
and discrimination in the yeast MAPK network
Attila Reményi, Matthew C. Good, Roby P. Bhattacharyya, and Wendell A. Lim
Molecular Cell 20, 951-962 (2005)
Rewiring MAP Kinase Pathways Using Alternative Scaffold Assembly Mechanisms
Sang-Hyun Park, Ali Zarrinpar, and Wendell A. Lim
Science 299, 1061-1064 (2003)
--
______________________________________
Wendell A. Lim, Ph.D.
Professor
Dept. of Cellular and Molecular Pharmacology
University of California, San Francisco
Genetech Hall - N412E
600 - 16th Street
San Francisco, CA 94143-2240
[EMAIL PROTECTED]
Phone: 415-502-8080
FAX: 415-514-4242
http://www.ucsf.edu/limlab
