[ccp4bb] Protein Crystallographer (R5-R7) - St. Louis, MO

[Charles Ballard]

Pfizer Global Research in St. Louis currently has an opening for a highly motivated and talented protein crystallographer to join our Structural & Computational Chemistry Department.  The successful candidate will become a member of a productive and innovative structure based drug design group, working within cross-functional structural biology teams to solve structures of new drug targets and generate protein-ligand co-crystal structures.  As a member of several drug discovery project teams, you will have an opportunity to partner with a wide variety of researchers, including medicinal chemists, biologists, and computational chemists to leverage structural information to direct the optimization of lead chemical matter into potential drug candidates.  The successful candidate will be expected to design protein constructs for crystallization, partner with biochemists involved in protein purification, guide crystallization experiments, collect X-ray diffraction data on home and synchrotron sources, determine and interpret crystal structures, and leverage these structure results in structure based design efforts.  Additionally, there will be a significant role in identifying new targets for structural studies and new technologies or approaches to enhance the efficiencies of X-ray crystallography methods within the group.   Qualifications:     •Ph.D. in Biochemistry, Chemistry, or equivalent with 3-5 years post-PhD experience in protein crystallography •Ability to independently guide reagent and crystallization efforts for protein crystallography projects. •Experience in protein purification, biophysical analysis of proteins, crystallization,  novel phasing methods or high throughput crystallography.    •Ability to successfully partner with colleagues of various disciplines. •Excellent written and verbal communication skills.     Job Requisition #: 71197   To learn more about our people, our products, and our plans for the future, visit www.pfizer.com/careers

Protein Crystallographer.doc- Req# 71197.doc
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Protein Crystallographer.doc- Req# 71197.doc
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