Dear all, Could you explain two terms of "Accessible Surface Area"(ASA) and "Buried Surface Area"(BSA) of PISA at EBI ?
I thought that Standard accessible surface area = Solvent accessible surface area + Buried surface area. When I looked up the result of PISA, ASA is always bigger than BSA except "inaccessible residues". Thus, I think that ASA of PISA means that "Standard accessible surface area" but one weird thing is that those values of same type residues,i.e. Ala, are quite varied among one chain. Also, "Inaccessible residues" has 0.00 square angstrom for both ASA and BSA. How can this happen? I believe that ASA should be bigger than 0.00, for instance, 100 angstrom square. Best, Hyunchul Kim Ph.D candidate Bioinformatics program Keio University, Japan
