Dear CCP4,
I have a couple of datasets native and heavy-atom-derivatized. The spacegroup
and cell dimensions of all are the same (or very similar). For some reason
I cannot merge any of the datasets together. If for example I rescale one
native dataset by itself, my Rmerge is about 10%, but when I add 50 images (or
so) of another, supposedly isomorphous crystal, my Rmerge goes up to 20%.
I was wondering if anyone has encountered a similar problem or can offer any
suggestions. Thanks so much,
Kianoush
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