Dear All,

We have a tetrameric structure solved at 2.3A resolution. In one molecule of the tetramer, a loop of 10 amino acids length, has two conformations with 6-8A distance with each other with occupance of ~0.5 each (something like one is closed and other is open conformation). How to represent this two alternate conformations in the PDB record and how to refine with refmac?

Thanks for your kind help

With regards
Karthik

Reply via email to