On Nov 3 2007, Randy J. Read wrote:
Depends on the purpose. From the LLG, I want to see that it is positive (negative means that I'm being too optimistic about the quality of the model, i.e. the RMS error is higher or the completeness lower than assumed), and I would like to see it increase as the solution becomes more complete (i.e. RF score increases with TF, which increases for RF on second molecule, and so on). But to assess the significance of a solution, I'd place more weight on the LLG.
Oops! Tassos just pointed out my slip here. I'd meant to say that to assess the significance of a solution, I'd place more weight on the Z-score, not the LLG.
Randy Read
