Dear all,
I'm wondering what's the best way to add an extra (tighter) distance
restraint on the linkage
between the P-atom of a guanidine (Gd)-residue and the O3'-atom of a
thymidine (Td)-residue in an oligonucleotide structure,
with use of the program Refmac_5.2.0019 (ccp4-6.0.2)...?
And is it possible to specify this restraint for only two particular
residues (e.g. T1 and G2)..?
Many thanks
Regards
Kristof
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Kristof Van Hecke, PhD
Biomoleculaire Architectuur
Celestijnenlaan 200 F
B-3001 Heverlee (Leuven)
Tel: +32(0)16327477
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