Dear All

This current vacancy may be of interest to final year PhD or recently postdoctoral researchers.

Best wishes

Peter Leadlay

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Professor Peter Leadlay, University of Cambridge, Department of Biochemistry, Cambridge CB2 1GA, UK.

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HERCHEL SMITH POSTDOCTORAL RESEARCH FELLOWSHIP IN BIOCHEMISTRY(Structural Biology /Biosynthesis), UNIVERSITY OF CAMBRIDGE

This post is one of nine research fellowships being advertised in the 20th December 2007 issue of Nature, as well as on jobs.ac.uk. The closing date has been set for applications as 17th January. For this particular post, the Herchel Smith Fellow will be expected to carry out his/her independent laboratory-based research programme within the Department of Biochemistry and accommodated within the laboratory space of the Herchel Smith Professor of Biochemistry, Professor Peter Leadlay FRS.

The successful applicant will be expected to work on some aspect of the biosynthesis and biochemistry of antibiotic natural products, especially polyketides, i.e. within the general field of Antibiotic Biosynthesis. Applications are particularly encouraged from candidates wishing to study structure-activity relationships of key biosynthetic enzymes including use of X-ray crystallography and other biophysical approaches for structural analysis.

However, the area of research within which the appointment will be made also includes the molecular microbiology and genetics of actinomycetes; the elucidation of novel biosynthetic pathways and their regulation; the engineering of pathways for overproduction of specific metabolites and for production of novel, potentially clinically useful metabolites, using either knowledge-based approaches or directed evolution; and studies to determine novel cellular targets and mechanisms of action of natural products.

Those interested in applying are encouraged to visit the Department's website at http//www.gen.cam.ac.uk as well as that of the School of the Biological Sciences at http//www.bio.cam.ac.uk, and the Leadlay website at http://www.bio.cam.ac.uk/~pflgroup/index.html.

Informal enquiries may be addressed to Professor Leadlay at [EMAIL PROTECTED], or, on practical aspects of the Scheme, to Jürgen Wastl ,Administrative Officer (RAE) Academic Division, University of Cambridge,
The Old Schools, Trinity Lane, Cambridge CB2 1TT
"Juergen Wastl" <[EMAIL PROTECTED]>

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