Just for the record, if you feed the data into XPREP (using Tim Gruene's 
mtz2sca if necessary) it will almost certainly give you the choice of 
space groups - with an indication of which is the most likely - and do 
the necessary cell and index transformations automatically. I recommend 
inputting unmerged data in such cases!

George

Prof. George M. Sheldrick FRS
Dept. Structural Chemistry,
University of Goettingen,
Tammannstr. 4,
D37077 Goettingen, Germany
Tel. +49-551-39-3021 or -3068
Fax. +49-551-39-2582


On Fri, 7 Mar 2008, Pietro Roversi wrote:

> Dear all,
>                after much sweat and grief I managed to index my data in
> P321 but looking at the symmetry I think they might be C2: reindexing
> from P321 to C2 with the 2h+k, k, l operator in sortmtz produces the
> right cell (and yes I did tick the "Reduce reflexions to the asymmetric
> unit" button so that noreduce is not among the sortmtz keywords): 
> 
> P321 209.3168  209.3168   40.6822   90.0000   90.0000  120.0000
> C2 362.5473  209.3168   40.6822   90.0000   90.0000   90.0000
> 
> But: scala then decides that the asymmetric unit is not the right one
> and it mysteriously changes cell parameters (which I think points to a
> bug in the sortmtz process of reindexing):
> 
> Reciprocal space symmetry: 
> Space group: "C 1 2 1" Point group: "PG2" Laue group: "2/m" 
> Reference asymmetric unit: "k>=0 and (l>0 or (l=0 and h>=0))" 
>   (change of basis may be applied) 
> 
> and I end up with this C2 cell in the mtz output from scala:
> 
> 285.9320  285.9320   40.6824   90.0000   90.0000   90.0000
> 
> I have tried OUTPUT ORIGINAL ans some such in scala but to no avail.
> 
> Now please don't all tell me to go back and reindex-reintegrate these
> images - although I might have to do it to get the best out of these
> data once I am convinced they are monoclinic. 
> 
> Rather, I would appreciate suggestions on what program to feed the
> multirecord mtz to sort its asymmetric unit in C2 so that scala does not
> play tricks on me; or what keyword to feed scala to keep reflexions in
> the current asymmetric unit (and use cad or sftools afterwards on the
> scaled/merged file)
> 
> Thanks
> 
> Pietro  
> 
> 
> 
> -- 
> Pietro Roversi
> Sir William Dunn School of Pathology, Oxford University
> South Parks Road, Oxford OX1 3ER, England UK
> Tel. 0044-1865-275385
> 

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