Hi,
Does anyone have a foolproof recipe for preparing one or more heavy
atom derivatives for a nice, easily crystallized protein like
lysozyme? I'm looking for something that I can use as a hands-on MIR/
SIR tutorial for beginning students. I'd rather the students be able
to focus their attention on data collection and analysis, rather than
spending a lot of time screening different soaks.
I have looked at Peter Sun's paper on quick soaking (Acta Cryst D58:
1092-1098, 2002), and will definitely try what they did; but any
other recipes would also be welcome.
Thanks,
Pat
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Patrick J. Loll, Ph. D.
Professor of Biochemistry & Molecular Biology
Director, Biochemistry Graduate Program
Drexel University College of Medicine
Room 10-102 New College Building
245 N. 15th St., Mailstop 497
Philadelphia, PA 19102-1192 USA
(215) 762-7706
[EMAIL PROTECTED]
