If you are using new version of refmac from www.ysbl.york.ac.uk/YSBLPrograms/index.jsp
then you can use harmonic restraints. Have a look for instructions: www.ysbl.york.ac.uk/refmac/data/refmac_news.html I hope it helps. regards Garib On 6 May 2008, at 16:39, Debasish Chattopadhyay wrote:
How to keep a ligand fixed during refinement using refmac? Debasish
