UNIVERSITY OF SUSSEX School of Life Sciences
Department of Chemistry and Biochemistry Postdoctoral Research Assistant in Protein Crystallography Applications are invited for a three year Postdoctoral position, funded by the MRC, in the laboratory of Dr. Darren Thompson. The successful candidate will work on the complement protein, C1. This will involve the use of X-ray crystallography and other biophysical techniques to investigate the structure and stability of this complex. The laboratory is situated on the Falmer campus, Brighton, set on the edge of the Sussex Downs, and just a few minutes away is the lively, friendly seaside town of Brighton with its great leisure facilities and its rich, eclectic cultural life. The Chemistry and Biochemistry department is well equipped for protein biophysics including: Circular dichroism (Jasco CD), and state of the art UV/Vis rapid scan and fluorescence /anisotropy /CD stopped-flow (Applied Photophysics p* and SX18MV stopped flow) and equilibrium fluorescence. Protein crystallography facilities include a RU-H3RHB rotating anode X-ray generator with Osmic max-Flux optics and RAXIS-IV image plate area detector and MSC cryo system facilities. Additional biophysics facilities including ITC and atomic force microscopy. There are also state of the art facilities for microarrays and the newly-created Sussex Centre for Advanced Microscopy provides state of the art facilities for confocal, 2-photon, and CCD microscopy, with fluorescence correlation and lifetime capabilities, a Hitachi7100 transmission electron microscope and cryo- and scanning electron microscopy. Applicants should have appropriate degrees and experience in protein biochemistry or protein crystallography and will hold a PhD, or have submitted their PhD thesis prior to taking up the appointment. The post is available immediately, for a period of three years, Please direct informal enquiries and CVs to Dr. Darren Thompson: [EMAIL PROTECTED]
