Hi Albert, Please refer to the following paper (and references therein) for a description of the four chloride located in the nucleosome structure..
1: Davey CA, Sargent DF, Luger K, Maeder AW, Richmond TJ. Solvent mediated interactions in the structure of the nucleosome core particle at 1.9 a resolution. J Mol Biol. 2002 Jun 21;319(5):1097-113. In the nucleosome structure, there are four locations where chloride ions are found. For example, one of the hydrated chlorides is found in a Van der Waal's cup of sorts formed by three amino acids (Met, Pro and Lys). See PDB id 1AOI, 1KX5 or 1S32. Hope that provides some info. Raji ---------Included Message---------- >Date: 10-jul-2008 11:47:59 -0400 >From: "Jacob Keller" <[EMAIL PROTECTED]> >To: <[email protected]> >Subject: Re: [ccp4bb] Anion binding sites in proteins > >I have been interested in this topic as well, so could any responses that are >not also addressed to the BB be sent to me as well? > >Thanks very much, > >Jacob Keller > >******************************************* >Jacob Pearson Keller >Northwestern University >Medical Scientist Training Program >Dallos Laboratory >F. Searle 1-240 >2240 Campus Drive >Evanston IL 60208 >lab: 847.491.2438 >cel: 773.608.9185 >email: [EMAIL PROTECTED] >******************************************* > > ----- Original Message ----- > From: Albert Guskov > To: [email protected] > Sent: Thursday, July 10, 2008 3:52 AM > Subject: [ccp4bb] Anion binding sites in proteins > > > Dear all, > can someone point me to something similar to Metal coordination sites in > proteins (http://tanna.bch.ed.ac.uk), but describing anions (I'm mainly interested in chloride-binding sites)? > Thank You, > Albert > -- > Albert Guskov, > Freie Universitaet Berlin > Fachbereich Biologie, Chemie, Pharmazie > Institut fur Chemie/Kristallographie > ---------End of Included Message----------
