Dear all,

I was refining a structure with a modified DNA base, and I generated a cif
file for that base using Dundee server with previously solved coordinates of
this base. However, when I refine with Refmac, the base has distorted angles
and bonds. I wonder how I can edit the cif file and restrain those
angles/bonds for Refmac refinement?

Thank you very much!

Best,
Melody

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