Dear all,
I am sure that being readers of the bulletin board you have run once
or twice across the ARP/wARP software suite - if for no other reason
reading the bug reports and the shameless promotions from my side,
recommending people to use it!
Well, there is still plenty of work to be done, and even for this over-
ten-year-old dinosaur of a software, we have many exciting plans! The
focus of the Amsterdam group (our better half resides at Hamburg with
Victor Lamzin) is in model completion: how can we arrive from the
fairly complete - but not 'final' - models of ARP/wARP in a model that
is as complete and correct as an expert crystallographer would
deliver? At the same time we are interested to improve the whole ARP/
wARP procedure, and we have created a control system we call flex-
wARP, which we want to develop further to a 'smart' decision making
system. Other current areas of interest include the use of 'supervised
learning' techniques for picking up or deleting 'free atoms' in
electron density maps, especially at low resolution.
The Amsterdam team collaborates closely with the Hamburg team of
Victor, which together develop and distribute ARP/wARP. The team is
located in our brand new lab space at the Netherlands Cancer
Institute, in close contact with the two lively Structural Biology
groups that are run by myself and Titia Sixma. The Structural Biology
groups operate in a state-of-the-art facility, with several nano-
crystallization and imaging robotics, data collection facilities and
include an extensive biophysical instrumentation setup. Other research
groups at the NKI are focused around many aspects of cancer biology,
but also include groups involved in bioinformatics, electron
microscopy, a high content screening facility, a protein facility, a
medical imaging group, and others. These together create a
scientifically stimulating environment, that extends well beyond
Structural Biology.
We are looking for an enthusiastic team member at the post-doctoral
level, who has some experience in X-ray crystallography and a good
working knowledge of programing, preferably in C++, python, c, Java or
even - alas - Fortran(*). I would be especially obliged if you could
also bring this to the attention of any colleagues that work on small
molecule crystallography or have a strong background in physics or
applied mathematics, are excellent programers, and might like to
consider working in this subject. The initial contract will be for up
to two years and can be renewed at the time depending on
circumstances. The position is available asap. Salaries are according
in NKI rules (FWG 55) and are not worse than most other post-doctoral
jobs outside the EMBL ...
For any further info please email me.
Tassos
(8) Experience in .NET will not be a plus.
