Hello all,
I have a structure from a non-natural fusion of the truncated C-
terminus of one protein with the truncated N-terminus of another. For
the deposition, we want to keep the numbering as found in the separate
proteins. It looks something like this:
1 12
| |
....HWVCKDIALLMCFFLEEMSEEP....
| |
754 763
At no point is there an overlap in numbering (i.e. the N-terminal
residue number is higher than the C-terminal residue number).
Is this numbering scheme supported by the PDB standard? Thus far, all
of the software seems to handle it (refmac, Coot, PyMOL, pdb_extract,
PDB precheck & validation, etc).
Can anyone see a reason to not deposit with this non-sequential
residue numbering?
~Todd