Postdoctoral Research Position (Photosynthesis and Light Signalling) School of Biological Sciences, Biosciences Building, Crown Street,University of Liverpool, Liverpool L69 7ZB
Background The aim of the research programme is to investigate the spectroscopic and structural properties of a number of macromolecules involved in photosynthesis within the non-sulphur purple bacterium Rps. palustris. The bacterium is actively being studied by a number of groups as a model for CO2 uptake, a source of bio-fuels and a possible role for bioremediation. The photosynthetic apparatus comprises LH1-RC complex, the peripheral LH2 complexes and a novel LH4 complex which is adapted to low-light conditions. The structure of LH4 will help to understand how solar energy is trapped efficiently when light intensities are low. The information maybe used to design better solar cells. A number of light sensing bacteriophytochromes (Bphs) are found in this bacterium, four of which control the expression of photosynthetic genes. Two Bphs control the expression of LH4 while another controls a large cluster of genes that encode for enzymes responsible for chromophore biogenesis and for t! he synthesis of LH1 and RC complex polypeptides. A number of Bphs constructs have been cloned and purified while LH4, which is a membrane protein, has been purified from photosynthetic membranes. Bphs and LH4 have been crystallised and are currently being studied. There are also opportunities for contributing to dynamics studies by time resolved spectroscopy. Role/Work Programme The applicant will be expected to contribute to various parts of the project, such as sample purification, crystal growth, X-ray diffraction experiments and time resolved spectroscopy experiments. Data will be collected at facilities such as DIAMOND and CLF. If some of the experimental methods are new to the candidate there will be an opportunity to learn the techniques. Personal Skills and Attributes Required The applicant should have a PhD in a relevant biological subject and experience in protein purification is important. Post-doctoral experience would be beneficial but not essential. Good computer skills and a working knowledge of protein crystallography packages will be an advantage. The project is broad ranging in its scope and an ability to think creatively and to explore new research directions is important. To obtain an application form and further details follow the link bellow. For informal enquiries please email [EMAIL PROTECTED] Ref: R-568895 http://www.liv.ac.uk/working/job_vacancies/research/R-568895.htm Closing date for receipt of applications: 9 January 2009 The University of Liverpool is and equal opportunity employer.
