A postdoctoral position is available in the lab of Filip Van Petegem at the University of British Columbia.
Our lab focusses on calcium channels in both the plasma membrane and intracellular compartments. Calcium is an important 2nd messenger and channels allowing influx of calcium into the cytoplasm play major roles in the contraction of cardiac and skeletal muscle, pacemaking in the heart, release of neurotransmitters and hormones, and activation of the immune system. Mutations in these channels lead to severe genetic diseases and they are major drug targets for treating cardiac diseases, epilepsy, and chronic pain. We use an integrated approach to understand how calcium channels function, including electrophysiology, X-ray crystallography, calorimetry, and various additional biophysical techniques. An overview of our research can be found at http://crg.ubc.ca/VanPetegem. Our lab is part of the cardiovascular research group (http://crg.ubc.ca), and is housed in the new life sciences centre at UBC. We are looking for a highly motivated individual with a sincere interest in the field of ion channels or neuroscience, and with experience in crystallizing and solving structures of proteins. Alternatively, individuals with strong electrophysiological skills and wishing to learn crystallography are also encouraged to apply. Both formal applications and informal enquiries can be addressed via email to: [email protected] Sincerely, Filip Van Petegem -- Filip Van Petegem, PhD Assistant Professor The University of British Columbia Dept. of Biochemistry and Molecular Biology 2350 Health Sciences Mall - Rm 2.356 Vancouver, V6T 1Z3 phone: +1 604 827 4267 email: [email protected] http://crg.ubc.ca/VanPetegem/
